Sponsor Gives All Applicable Chemistry

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Sponsor Gives All Applicable Chemistry

Vanessa 0 5 02.11 21:57

If the chosen hemp manufacturer holds a Drug Grasp File (DMF), the sponsor must obtain a Letter of Authorization (LOA) to reference CMC and BRM information. Alternatively, an IND submission would need to contain all needed CMC data characterizing their research drug and guaranteeing it is protected to be used in humans. The sponsor sends a duplicate of the IND and clinical protocol, together with a LOA (if applicable), to FDA. FDA evaluations the submitted IND. The sponsor must wait 30 calendar days following IND submission before initiating any clinical trials, until FDA notifies the sponsor that the trials may proceed sooner. During this time, FDA has a possibility to evaluate the submission for security to guarantee that research topics won't be subjected to unreasonable threat.


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