Pe 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults. Neuroimage Clin. 2014;5:36?1. 58. Conti JB, Sears SF. Cardiac resynchronization therapy: can we make PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/14960617 our heart failure patients smarter? Trans Am Clin Climatol Assoc. 2007;118:153?4. 59. Kalaria VG, Passannante MR, Shah T, Modi K, Weisse AB. Effect of mitral regurgitation on left ventricular 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole thrombus formation in dilated cardiomyopathy. Am Heart J. 1998;135:215?0. 60. Al-Khadra AS, Salem DN, Rand WM, Udelson JE, Smith JJ, Konstam MA. Antiplatelet agents and survival: a cohort analysis from the Studies of Left Ventricular Dysfunction (SOLVD) trial. J Am Coll Cardiol. 1998;31:419?5. 61. Freudenberger RS, Hellkamp AS, Halperin JL, Poole J, Anderson J, Johnson G, et al. Risk of thromboembolism in heart failure: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT). Circulation. 2007;115:2637?1. 62. Quinn TJ, Gallacher J, Deary IJ, Lowe GD, Fenton C, Stott DJ. Association between circulating hemostatic measures and dementia or cognitive63.64. 65.66.67.68.69.70.71.72.73.impairment: systematic review and meta-analyzes. J Thromb Haemost. 2011;9:1475?2. Hanon O, Vidal JS, de Groote P, Galinier M, Isnard R, Logeart D, et al. Prevalence of memory disorders in ambulatory patients aged >/=70 years with chronic heart failure (from the EFICARE Study). Am J Cardiol. 2014;113:1205?0. Davis KK, Allen JK. Identifying cognitive impairment in heart failure: a review of screening measures. Heart Lung. 2013;42:92?. Quinn TJ, Fearon P, Noel-Storr AH, Young C, McShane R, Stott DJ. Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within community dwelling populations. Cochrane Database Syst Rev. 2014;4:CD010079. Sink KM, Leng X, Williamson J, Kritchevsky SB, Yaffe K, Kuller L, et al. Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study. Arch Intern Med. 2009;169:1195?02. Solfrizzi V, Scafato E, Frisardi V, Seripa D, Logroscino G, Kehoe PG, et al. Angiotensin-converting enzyme inhibitors and incidence of mild cognitive impairment. The Italian Longitudinal Study on Aging. Age (Dordr). 2013;35:441?3. Levi MN, Macquin-Mavier I, Tropeano AI, Bachoud-Levi AC, Maison P. Antihypertensive classes, cognitive decline and incidence of dementia: a network meta-analysis. J Hypertens. PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/9544797 2013;31:1073?2. Korte SM, Korte-Bouws GA, Koob GF, De Kloet ER, Bohus B. Mineralocorticoid and glucocorticoid receptor antagonists in animal models of anxiety. Pharmacol Biochem Behav. 1996;54:261?. Packer M, Califf RM, Konstam MA, Krum H, McMurray JJ, Rouleau JL, et al. Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat 4,4,5,5-Tetramethyl-2-(2-methylprop-1-en-1-yl)-1,3,2-dioxaborolane Versus Enalapril Randomized Trial of gahmj.2015.132 Utility in Reducing Events (OVERTURE). Circulation. 2002;106:920?. McMurray JJV, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, et al. Angiotensin eprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371:993?004. Madani R, Poirier R, Wolfer DP, Welzl H, Groscurth P, Lipp HP, et al. Lack of neprilysin suffices to generate murine amyloid-like deposits in the brain and behavioral deficit in vivo. J Neurosci Res. 2006;84:1871?. Kubo T, Sato T, Noguchi T, Kitaoka H, Yamasaki F, Kamimura N, et al. Influences of donepezil on cardiovascular system - possible therapeutic.